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聚乙二醇-NHS酯 ‍Creative PEGWorks 高分子试剂 PEG-NHS/NHS ester PEG
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聚乙二醇-NHS酯 ‍Creative PEGWorks 高分子试剂 PEG-NHS/NHS ester PEG
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品牌: Creative PEGWorks
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聚乙二醇-NHS酯

NHS ester PEG

Catalog No.Product name & molecular weight

mPEG-SCM (PEG-NHS: Succinimidyl Carboxyl Methyl ester)

甲氧基-聚乙二醇-琥珀酰亚胺NHS酯

PJK-208mPEG-SCM, MW 350
PJK-209mPEG-SCM, MW 550
PJK-210mPEG-SCM, MW 10000
PJK-211mPEG-SCM, MW 30000
PJK-212mPEG-SCM, MW 20000
PLS-213mPEG-SCM, MW 5000
PLS-214mPEG-SCM, MW 2000
PLS-215mPEG-SCM, MW 1000
PLS-216mPEG-SCM, MW 40000

mPEG-SC (Methoxy PEG Succinimidyl Carbonate NHS Ester)

甲氧基-聚乙二醇-琥珀酰亚胺碳酸酯

PLS-510mPEG-SC, MW 350
PLS-511mPEG-SC, MW 550
PLS-512mPEG-SC, MW 1k
PLS-513mPEG-SC, MW 2k
PLS-514mPEG-SC, MW 5k
PLS-515mPEG-SC, MW 10k
PLS-516mPEG-SC, MW 20k
PLS-517mPEG-SC, MW 30k
PLS-518mPEG-SC, MW 40k

mPEG-SG (PEG-NHS: Succinimidyl Glutarate ester)

甲氧基-聚乙二醇-琥珀酰亚胺戊二酸酯

PSB-216mPEG-SG, MW 30,000
PSB-2160mPEG-SG, MW 40,000
PSB-217mPEG-SG, MW 20,000
PSB-218mPEG-SG, MW 550
PSB-219mPEG-SG, MW 10,000
PSB-220mPEG-SG, MW 5,000
PSB-221mPEG-SG, MW 2,000
PSB-222mPEG-SG, MW 1,000

mPEG-SS (PEG-NHS: Succinimidyl Succinate ester)

甲氧基-聚乙二醇-琥珀酰亚胺琥珀酸酯

PSB-2100mPEG-SS, MW 550
PSB-2101mPEG-SS, MW 1,000
PSB-2102mPEG-SS, MW 2,000
PSB-2103mPEG-SS, MW 5,000
PSB-2104mPEG-SS, MW 10,000
PSB-2105mPEG-SS, MW 20,000
PSB-2106mPEG-SS, MW 30,000
PSB-2107mPEG-SS, MW 40,000

mPEG-GAS (Glutaramide Succinimidyl ester)

甲氧基-聚乙二醇-戊酰胺琥珀酰亚胺酯

PSB-2080mPEG-GAS, MW 550
PSB-2081mPEG-GAS, MW 1,000
PSB-2082mPEG-GAS, MW 2,000
PSB-2083mPEG-GAS, MW 5,000
PSB-2084mPEG-GAS, MW 10,000
PSB-2085mPEG-GAS, MW 20,000
PSB-2086mPEG-GAS, MW 30,000
PSB-2087mPEG-GAS, MW 40000

mPEG-SAS (PEG NHS: Succinamide Succinimidyl ester)

甲氧基-聚乙二醇-琥珀酰胺琥珀酰亚胺酯

PSB-2110mPEG-SAS, MW 550
PSB-2111mPEG-SAS, MW 1,000
PSB-2112mPEG-SAS, MW 2,000
PSB-2113mPEG-SAS, MW 5,000
PSB-2114mPEG-SAS, MW 10,000
PSB-2115mPEG-SAS, MW 20,000
PSB-2116mPEG-SAS, MW 30,000
PSB-2117mPEG-SAS, MW 40,000

SG-PEG-SG (Bifunctional PEG Succinimidyl Glutarate NHS ester)

琥珀酰亚胺戊二酸酯-聚乙二醇-琥珀酰亚胺戊二酸酯

PSB-308SG-PEG-SG, MW 35k
PSB-309SG-PEG-SG, MW 600
PSB-310SG-PEG-SG, MW 1k
PSB-311SG-PEG-SG, MW 2k
PSB-312SG-PEG-SG, MW 3.4k
PSB-313SG-PEG-SG, MW 5k
PSB-314SG-PEG-SG, MW 10k
PSB-315SG-PEG-SG, MW 20k

SS-PEG-SS (Bifunctional PEG Succinimidyl Succinate NHS ester)

琥珀酰亚胺琥珀酸酯-聚乙二醇-琥珀酰亚胺琥珀酸酯

PSB-3300SS-PEG-SS, MW 600
PSB-3301SS-PEG-SS, MW 1k
PSB-3302SS-PEG-SS, MW 2k
PSB-3303SS-PEG-SS, MW 3.4k
PSB-3304SS-PEG-SS, MW 5k
PSB-3305SS-PEG-SS, MW 10k
PSB-3306SS-PEG-SS, MW 20k

GAS-PEG-GAS (Bifunctional PEG Succinimidyl ester NHS-PEG-NHS)

戊酰胺琥珀酰亚胺酯-聚乙二醇-戊酰胺琥珀酰亚胺酯

PSB-3310GAS-PEG-GAS, MW 600
PSB-3311GAS-PEG-GAS, MW 1k
PSB-3312GAS-PEG-GAS, MW 2k
PSB-3313GAS-PEG-GAS, MW 3.4k
PSB-3314GAS-PEG-GAS, MW 5k
PSB-3315GAS-PEG-GAS, MW 10k
PSB-3316GAS-PEG-GAS, MW 20k

SAS-PEG-SAS (Bifunctional PEG Succinimidyl ester NHS-PEG-NHS)

琥珀酰胺琥珀酰亚胺酯-聚乙二醇-琥珀酰胺琥珀酰亚胺酯

PSB-3320SAS-PEG-SAS, MW 600
PSB-3321SAS-PEG-SAS, MW 1k
PSB-3322SAS-PEG-SAS, MW 2k
PSB-3323SAS-PEG-SAS, MW 3.4k
PSB-3324SAS-PEG-SAS, MW 5k
PSB-3325SAS-PEG-SAS, MW 10k
PSB-3326SAS-PEG-SAS, MW 20k

SC-PEG-SC (Succinimidyl Carbonate PEG NHS Ester)

琥珀酰亚胺碳酸酯-聚乙二醇-琥珀酰亚胺碳酸酯

PSB-9010SC-PEG-SC, MW 600
PSB-9011SC-PEG-SC, MW 1k
PSB-9012SC-PEG-SC, MW 2k
PSB-9013SC-PEG-SC, MW 3.4k
PSB-9014SC-PEG-SC, MW 5k
PSB-9015SC-PEG-SC, MW 10k
PSB-9016SC-PEG-SC, MW 20k
PSB-9017SC-PEG-SC, MW 40k

HO-PEG-NHS (Hydroxyl PEG Succinimidyl NHS ester)

羟基-聚乙二醇-琥珀酰亚胺NHS酯

PHB-1910HO-PEG-NHS, MW 1k
PHB-1911HO-PEG-NHS, MW 2k
PHB-1912HO-PEG-NHS, MW 3.4k
PHB-1913HO-PEG-NHS, MW 5k
PHB-1914HO-PEG-NHS, MW 10k

Boc-NH-PEG-SCM (Boc protected amine PEG succinimidyl NHS ester)

Boc保护胺-聚乙二醇-琥珀酰亚胺NHS酯

PHB-966Boc-NH-PEG-SCM, MW 1k
PHB-967Boc-NH-PEG-SCM, MW 10k
PHB-968Boc-NH-PEG-SCM, MW 5k
PHB-969Boc-NH-PEG-SCM, MW 2k
PHB-970Boc-NH-PEG-SCM, MW 3.4k

Fmoc-NH-PEG-SCM (Fmoc protected Amine PEG Succinimidyl NHS ester)

Fmoc保护胺-聚乙二醇-琥珀酰亚胺NHS酯

PHB-972Fmoc-NH-PEG-SCM, MW 1k
PHB-973Fmoc-NH-PEG-SCM, MW 3.4k
PHB-974Fmoc-NH-PEG-SCM, MW 5k
PHB-975Fmoc-NH-PEG-SCM, MW 2k
PHB-976Fmoc-NH-PEG-SCM, MW 10k

MAL-PEG-SCM (Maleimide PEG Succinimidyl NHS acid ester)

马来酰亚胺-聚乙二醇-琥珀酰亚胺NHS酯

PHB-950MAL-PEG-SCM, MW 2k
PHB-951MAL-PEG-SCM, MW 3.4k
PHB-952MAL-PEG-SCM, MW 5k
PHB-953MAL-PEG-SCM, MW 10k
PHB-954MAL-PEG-SCM, MW 1k

OPSS-PEG-NHS (Orthopyridyl disulfide PDP PEG Succinimidyl ester)

领吡啶二硫化物-聚乙二醇-琥珀酰亚胺NHS酯

PHB-994OPSS-PEG-NHS, MW 1k
PHB-995OPSS-PEG-NHS, MW 2k
PHB-996OPSS-PEG-NHS, MW 3.4k
PHB-997OPSS-PEG-NHS, MW 5k
PHB-998OPSS-PEG-NHS, MW 10k
ACA-PEG-SCM (Acrylamide PEG NHS ester)
丙烯酰胺-聚乙二醇-琥珀酰亚胺NHS酯 末端双键
PHB-1970ACA-PEG-SCM, MW 2k
PHB-1971ACA-PEG-SCM, MW 3.4k
PHB-1972ACA-PEG-SCM, MW 5k
PHB-1973ACA-PEG-SCM, MW 10k
PHB-1974ACA-PEG-SCM, MW 1k

AC-PEG-SCM (Acrylate PEG Succinimidyl NHS ester)

丙烯酸酯-聚乙二醇-琥珀酰亚胺NHS酯 末端双键

PHB-960AC-PEG-SCM, MW 2k
PHB-961AC-PEG-SCM, MW 3.4k
PHB-962AC-PEG-SCM, MW 5k
PHB-963AC-PEG-SCM, MW 10k
PHB-964AC-PEG-SCM, MW 1k

Biotin-PEG-SCM (Biotin PEG Succinimidyl NHS ester)

生物素-聚乙二醇-琥珀酰亚胺NHS酯

PJK-1900Biotin-PEG-SCM, MW 2k
PJK-1901Biotin-PEG-SCM, MW 3.4k
PJK-1902Biotin-PEG-SCM, MW 5k
PJK-1903Biotin-PEG-SCM, MW 10k
PJK-1904Biotin-PEG-SCM, MW 1k

4-Arm PEG-SCM (Multi-arm - four arm - PEG Succinimidyl NHS ester)

4臂星形-聚乙二醇-琥珀酰亚胺NHS酯

PSB-4854-Arm PEG-SCM, MW 2k
PSB-4864-Arm PEG-SCM, MW 10k
PSB-4874-Arm PEG-SCM, MW 20k
PSB-4884-Arm PEG-SCM, MW 5k

4-Arm PEG-SC (Multi Armed PEG Succinimidyl Carbonate NHS Ester)

4臂星形-聚乙二醇-琥珀酰亚胺碳酸酯

PSB-44114-Arm PEG-SC, MW 2k
PSB-44124-Arm PEG-SC, MW 5k
PSB-44134-Arm PEG-SC, MW 10k
PSB-44144-Arm PEG-SC, MW 20k

4-Arm PEG-SG (Multi-arm - four arm - PEG Succinimidyl Glutarate)

4臂星形-聚乙二醇-琥珀酰亚胺戊二酸酯

PSB-4604-Arm PEG-SG, MW 2k
PSB-4614-Arm PEG-SG, MW 10k
PSB-4634-Arm PEG-SG, MW 5k
PSB-4654-Arm PEG-SG, MW 20k

4-Arm PEG-SS (Multi-arm - four arm - PEG Succinimidyl Succinate)

4臂星形-聚乙二醇-琥珀酰亚胺琥珀酸酯

PSB-40104-Arm PEG-SS, MW 2k
PSB-40114-Arm PEG-SS, MW 5k
PSB-40124-Arm PEG-SS, MW 10k
PSB-40154-Arm PEG-SS, MW 20k

4-Arm PEG-GAS (Multi-arm - four arm - PEG Succinimidyl NHS ester)

4臂星形-聚乙二醇-戊酰胺琥珀酰亚胺酯

PSB-40204-Arm PEG-GAS, MW 2k
PSB-40214-Arm PEG-GAS, MW 5k
PSB-40224-Arm PEG-GAS, MW 10k
PSB-40254-Arm PEG-GAS, MW 20k

4-Arm PEG-SAS (Multi-arm - four arm - PEG Succinimidyl NHS ester)

4臂星形-聚乙二醇-琥珀酰胺琥珀酰亚胺酯

PSB-40304-Arm PEG-SAS, MW 2k
PSB-40314-Arm PEG-SAS, MW 5k
PSB-40324-Arm PEG-SAS, MW 10k
PSB-40354-Arm PEG-SAS, MW 20k

8-Arm PEG-SCM (Multi-arm - eight arm - PEG Succinimidyl NHS ester)

8臂星形-聚乙二醇-琥珀酰亚胺NHS酯

PSB-8418-Arm PEG-SCM, MW 10k
PSB-8428-Arm PEG-SCM, MW 20k
PSB-8448-Arm PEG-SCM, MW 40k

8-Arm PEG-SG (Multi-arm - eight arm - PEG Succinimidyl NHS ester)

8臂星形-聚乙二醇-琥珀酰亚胺戊二酸酯

PSB-8468-Arm PEG-SG, MW 10k
PSB-8478-Arm PEG-SG, MW 20k
PSB-8498-Arm PEG-SG, MW 40k

8-Arm PEG-SS (Multi-arm - eight arm - PEG Succinimidyl NHS ester)

8臂星形-聚乙二醇-琥珀酰亚胺琥珀酸酯

PSB-80418-Arm PEG-SS, MW 10k
PSB-80428-Arm PEG-SS, MW 20k
PSB-80448-Arm PEG-SS, MW 40k

8-Arm PEG-GAS (Multi-arm - eight arm - PEG Succinimidyl NHS ester)

8臂星形-聚乙二醇-戊酰胺琥珀酰亚胺酯

PSB-80518-Arm PEG-GAS, MW 10k
PSB-80528-Arm PEG-GAS, MW 20k
PSB-80548-Arm PEG-GAS, MW 40k

8-Arm PEG-SAS (Multi-arm - eight arm - PEG Succinimidyl NHS ester)

8臂星形-聚乙二醇-琥珀酰胺琥珀酰亚胺酯

PSB-80618-Arm PEG-SAS, MW 10k
PSB-80628-Arm PEG-SAS, MW 20k
PSB-80648-Arm PEG-SAS, MW 40k

C18-PEG4-NHS (Tetraethylene glycol octadecyl succinimidyl ester)

十八烷-低聚四乙二醇-NHS酯

PMD-7005C18-PEG4-NHS, PEG MW 176 Da

C18-PEG6-NHS (Hexaethylene glycol octadecyl succinimidyl ester)

十八烷-低聚六乙二醇-NHS酯

PMD-7025C18-PEG6-NHS, PEG MW 264 Da

C18-PEG12-NHS (Dodecaethylene glycol octadecyl succinimidyl ester)

十八烷-低聚十二乙二醇-NHS酯

PMD-7045C18-PEG12-NHS, PEG MW 528 Da
Pyrene-PEG-NHS Ester
芘-聚乙二醇-NHS酯
PBL-9031Pyrene-PEG-NHS Ester, MW 1k
PBL-9032Pyrene-PEG-NHS Ester, MW 2k
PBL-9033Pyrene-PEG-NHS Ester, MW 3.4k
PBL-9034Pyrene-PEG-NHS Ester, MW 5k
PBL-9035Pyrene-PEG-NHS Ester, MW 10k

Acetal-PEG-NHS (Protected Aldehyde PEG NHS Ester)

缩醛-聚乙二醇-NHS酯

PJK-1701Acetal-PEG-NHS, MW 1k
PJK-1702Acetal-PEG-NHS, MW 2k
PJK-1703Acetal-PEG-NHS, MW 3.4k
PJK-1704Acetal-PEG-NHS, MW 5k
PJK-1705Acetal-PEG-NHS, MW 10k



Q: What are the differences among your PEG NHS ester & PEG Acid products?
A: We offer a variety of PEG Acid and PEG NHS ester. These NHS esters react with primary and secondary amine to form a stable amide linkage. This reaction may be carried out in an organic solution with an organic base or may be carried out in an aqueous solution at or around neutral pH or slightly acidic or basic. To PEGylate proteins or nanoparticles, it often requires a large excess of PEG NHS esters due to the competitive hydrolysis reaction in an aqueous solution. Stability of NHS esters is compared by their hydrolysis half-life (T1/2). To mitigate the competitive hydrolysis reaction, organic solvents such as amine-free, anhydrous DMF and DMSO may be used in combination with an aqueous buffer solution.

PEG NHS

esters

Structural characteristics

Amine

reactivity

Stability
Type A: SCMMethylene (CH2) linkage between PEG and NHS esterHighly reactiveHydrolysis half-life: less than five minutes. It often requires the use of a large excess of PEG reagents.
Type B: SGC4 aliphatic ester linkage between PEG and NHS esterVery reactiveHydrolysis half-life: around 20 minutes.
Type C: SSC3 aliphatic ester linkage between PEG and NHS esterVery reactiveHydrolysis half-life: around 10 minutes.
Type D: GASC4 aliphatic amide linkage between PEG and NHS esterVery reactiveHydrolysis half-life: around 20 minutes.
Type E: SASC3 aliphatic amide linkage between PEG and NHS esterVery reactiveHydrolysis half-life: around 10 minutes.

SCM: Succinimidyl Carboxyl Methyl ester; SG: Succinimidyl Glutarate ester; SS: Succinimidyl Succinate ester; GAS: GlutarAmide Succinimidyl ester; SAS: SuccinAmide Succinimidyl ester. Note: hydrolysis half-life depends on pH, temperature and other factors of the testing conditions.

PEG acidsStructural characteristics
Type A: AAMethylene (CH2) linkage between PEG and acid (COOH)
Type B: GAC4 aliphatic ester linkage between PEG and acid (COOH)
Type C: SAC3 aliphatic ester linkage between PEG and acid (COOH)
Type D: GAAC4 aliphatic amide linkage between PEG and acid (COOH)
Type E: SAAC3 aliphatic amide linkage between PEG and acid (COOH)
AA: Acetic Acid, also called CM - Carboxyl Methyl; GA: Glutaric Acid; SA: Succinic Acid; GAA: GlutarAmide Acid; SAS: SuccinAmide Acid.



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